For this Organic blog, we are supposed to look up at least one electrophilic aromatic substitution, which is also known as (EAS) step and talk about the step in detail. After looking I found a journal titled “Regioselective Electrophilic Aromatic Substitution Reactions over Reusable Zeolites” and the authors are Keith Smith and Gamal A. El-Hiti. The article discusses how electrophilic aromatic substitution reactions are very useful in many synthetic processes, for example aromatic compounds are versatile chemical feedstocks for a wide range of industrial products, such as, pharmaceutical, agrochemicals, dyestuffs and explosives. Also talked about how nitration of aromatic compounds is one of the most important and widely studied chemical reactions. Acetyl nitrate, which is a mixture of acetic anhydride and nitric acid, was the most useful possibility. The equation looked like this:
Ac2O + HNO3 ↔ AcONO2 + AcOH
After there compounds were nitrated there yields were excellent and with high rigoselectivity under mild conditions, using stoichiometric quantities of nitric acid and acetic anhydride, which was scheme 2 shown in the journal. Also Table 1, clearly shows how high the yields were. Overall, this article was very interesting and especially helpful with aromatic electrophilic substitution.
Resources/Citation:
Smith, Keith.; El-Hiti, Gamal A.; Regioselective Electrophilic Aromatic Substitution Reactions over Reusable Zeolites. EBSCOhost [Online] 2006, Vol. 10 Issue 13, 1603-1625. http://0-web.ebscohost.com.library.acaweb.org/ehost/detail?hid=21&sid=7ebb5565-9af3-4163-9ff3-aa040d029e1c%40sessionmgr13&vid=5&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=22631648 (accessed 2006)
Personally I feel like this was somewhat of an intense or more difficult than usual blog assignment. However, you seem to have taken the assignment and while it may be simple it is complete and that is the more important thing. You described the articles content, but you did not really describe what they were looking for, which is something I forgot to do as well. Also I feel like your blog is needing some more information on the reaction itself. Yes we needed to know about the article but at the same time the assignment is over EAS and there should be a little more discussion over the reaction.
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